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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af2ddb36133b27a4a6934bcdb14bc584bc7f717f633b14dfa0bc0006436a87f0' 
  AND token = '3UeZwy2WsBN+CKGyh7TVJbhLbaQZ6ASNjXW70edwkKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}