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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcd376618efc804229b6e3bb00f62361d19502d87464b4c470f0b0ef4f3bd4f1' 
  AND token = 'vBu0BtHJ30OXO3t5Wb6eUia3VzX9BLJ2IcV0XlvMOT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}