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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3786151d4d8b15da7777195fd54ebc1aabbdfed3f19b33913e43fc68bf891027' 
  AND token = 'DNfALYFqu7HNoh8L5sOBlqOLueeayt7qaVegPoL6Xmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}