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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b46e15fa4e4ad1b4eeeb22c29c4dc6494065cc53dafeb71908b757158c5088f' 
  AND token = 'uuBykXfanyX+Bk+s+1jv/xI5XWASPOoLfkTdn69kF+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}