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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650dacd41ec5e8e42273d05b633c48c171753ae9131a9d813d5da956b13c6e98' 
  AND token = 'y3sH4AAQaukuDUOCzxFkcjG7b9onKQduCVeS0SEl9WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}