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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed48c73f653cd390a7b41502de5253f910ee771e9daff49901a1645119cae0a6' 
  AND token = 'TcjgDbB/k9zgQ140nqcpocQdfzJuB7tpDP135BsTSsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}