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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1427e03dd5db123ecda54fd0276241e5cf4ee94596271c1da2d85c61ab0d4a6d' 
  AND token = 'QwFDCNmbJVwTNaI7+n5ECorHLOwE2v6sivPcJz6K/QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}