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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc80d76c916162563204feffc09b80a44e4157fa5cee4d258581aa03ac1af35c' 
  AND token = 's8yDBwToeRRAVqbJcWTjFHJcRAc43oy7uJ7OhDY74ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}