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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459a04fbd101bc5eadda5536ddabf1f4e64df5ee148d66f700a3f0c3b5e51020' 
  AND token = 'iMuxmvt2uqoTaRIQa8ASBWRP3idJllZv4ACgX5hwf5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}