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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd75f60209b2e17247360b9ee5793bd99dd65d2c96147402a4dd01d6c4741a5d' 
  AND token = 'g0rSPZ/YB+tEH3EhmktzwBhSULeMCxjwAOvL6mOhCy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}