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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a365d8077315086ebcfab65eaa634747b195900f051f80a04a0caca3aee2521' 
  AND token = 'xT/ks9xBJ/KxMh3nghBIT1y+LG9PegvZQdn3YZG9f3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}