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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c38c5e7fc67fffe54deccd7b0423cf74960d9e4ffe80d89728761adfa2254b4' 
  AND token = 'YONGWtMwnLMffe5B+UURPk7LR+exdRmB+eSZhfMTpdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}