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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3e2bb81d092a353392b15d596eb7b93e2c8b8537ba3726e8df1289ef1461365' 
  AND token = '2VxdrQdHc0Xv+DMon7y34ByU9+sKXmFmgFFOWpZ2sIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}