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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d9e749b751ed8a8bac5d464dd8806adaf3de5fe42df823e1db04be889c91f25' 
  AND token = '8IWzvl/hciCJs98nfgx/DX8rfHJckrcabWhRsxDBmYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}