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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80232617b101d6628f960b6ecc8eebbdcf2fc850cac88f102d3b0b39f38bf736' 
  AND token = 'bTdWbckKC8WTd4uXSMiqNTm2Gv2ly7lW6Esoa+R6fUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}