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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe9f7e995ca79fd40b2569950c50573e092be255be786bec401b14e70c309bf' 
  AND token = 'romxBO+8PMkJ3L421Mq2thyfTXKBtPBsW3AhQloBwOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}