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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06dc910c62c35e5212f5be50542575db44e4913f354b0b21aaba01095df598b4' 
  AND token = '5drRFJqIrh909Gmbj2rwe2cIDKpDSewiEEnFbPVA5GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}