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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9660375db8cdb95df5e47f35c1d9ff66c75dd4fb4208343cad78e4387f4b4a67' 
  AND token = '6Ky+PYJMxsyEmfdQlLvvWniwM8F4VJsZ6ZoMy5slMsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}