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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2a9fe486a923c373c2267e8f82568489e0c590730dbc407e1c9edbbd95e6085' 
  AND token = 'aPVIRl0Xbdhe9WkPvzmX9GPmGYeXdQf4yeXeFl6oaZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}