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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f6251aca685455944d4df670340df1155cd97008ad1d20d7cfb58463d19fcd3' 
  AND token = 'T7R2idtMDqsxsn+RRFPktSwDbWoNDCjv5Ibv2paBk/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}