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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a4319f283e832aa7788d06cdeaca2f179d65c104c9763e3103a9cb7c755502' 
  AND token = 'F2vmn4soY0dBDugwNF6M49G7x1zuwvVw1cmA+4/FCYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}