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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424514133de45f3dea2d19abd296954c50ef44b8a4d8416d75fca31f799fc882' 
  AND token = 'hUyLyPePQvdezDktsUhF1pumKcy1r36k//H4q+M9uFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}