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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6761b8ce7c853f867c019344c7f3fc26f7d64b264eb7f820748ef7a37ea99162' 
  AND token = 't5LUalfoR0/PC3EwBRI0UQTrHvK8S4ychSeTpOdvrfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}