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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e032341e59c0c5f04664d1409d4d4333b6418b8a555cf20715398d076c137f8d' 
  AND token = 'UEGctcgpUTv3CHMBitlL0853mIl185juGYyx10e1HcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}