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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5356659857b25bcf8359ea208d3ae22f007d2258d6c073415b8c4ed87a18b578' 
  AND token = '+XPdBmeL/4n4NCd6zvt25UAV4z2Fyi8zLEi8qbi5WdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}