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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66832f6b9832e7e23531f4111ec4a1c72e1bcef31d874c39c9c42676cff1a5db' 
  AND token = 'EKy1F+aCgavHjq0QoyIpj4BlH5zzs6gM0HlZtHo9oa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}