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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8336929b4597d331dda593a256fd38e6d507724cbb2ca38574d5ca9145e374f8' 
  AND token = '+tVEtOkKYXO4o+RXSrXhDILzdooble9zsf9Gy+AuWIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}