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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08e0d9aa1abef83c5f581ec125033b9d481d2b68c9a161d45d123cd542b1c3b8' 
  AND token = 'BPokS06OqPicFyx/3Wq5+FGjN8i2URJKUVlOrLFjGTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}