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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e76081c221fe487562f3e7eb9a04ec1b110932023b0006411ad525d0c18a1a3' 
  AND token = 'y+xLz5CnDkQ4ld2g39nSuh1aaYPvukFHiR8wTaODwiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}