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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4d26248d1cea75cdd6bb7276ac5db3191f904da832d2d6df2f9bdaacff0833' 
  AND token = 'dIWV0Z9WLE9UM7ubcwWREoZ6gbyDkYM0cVS6zDSAlko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}