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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f844d114a474e621ce4fa08f4d90666d7eb9385c9a66979dd27ba4c0bd2569e' 
  AND token = 'MXZ8kKzfwRklAzDKnFHfDBTAL1+QxU3MTF3htXPiocY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}