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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e30dd084ce8460f99250c5f4d2464117e98b3864ed34877a1e014a2577a36e7c' 
  AND token = 'EF1M3qtTLleB5qsFC729S8esMEs/8hAaw66VUabyAj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}