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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c580a166ca4b97431d0ab6b007cfa76ed0547a987e353e85a0fc38ce594a0ef' 
  AND token = '8/oP8ngs4qkRIJZpPe1EbcewUfTPEljXCFCO2aOjBBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}