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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18666a063335355eead8c542b169468ade0f8c38bfce44c32bb701f8d22376de' 
  AND token = 'kCii6/uKkcSYuXxz8+TTKKIJ8rftGbzQSYIOyQAQqJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}