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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5d4b4b6bf0a4a34a6dd3cc94c4527ab6272f0c00896fa1df45fa870d4f48a3' 
  AND token = 'o97kH3SzIoVyw4LNAiuvqZ6biGhsn4XyDkRWAlhMKMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}