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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e3490aca4ec5ad9679f7eaa20b2eb61036e7c737f0cb59a63daaab04e3b540' 
  AND token = 'PObYLd5QTXjs2tdAOvH2pFlURRTX32GOlDYcG5lIkbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}