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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54460365054146455a0ab7a2140e3fe27dbe92c4b19a4b7a67c207815a8537cd' 
  AND token = 'QxV2T58tXuf8AdOCYk3tHGUcAAu8ELaKeQeRZp64kiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}