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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ae332da9d8e46daee7d5a845d05a66dae3199aca4ea84b1ff4ac3fdb8929db' 
  AND token = '66aVmNMq/p7pvhDPnvUtRIe5+RwCS4iaTSNDEW45wnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}