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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db332fdc8b07871617fc72ee724b63c80eeb130f66ac8bb893a48ba0cab17171' 
  AND token = 'Ampx2pR1sdQnhAr6/+NPvdmC26y5q883B8fYFrbOF4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}