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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b80af78372ef0edf3865880b59a5a0ad076a04a1fe02ad0e4d2405cef1168fe' 
  AND token = '/e3M5s2XMYm5m+p4fvqiSBAuviTV3CXfC3UWCoJamN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}