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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad812426668dd90043efd019e4b59bc4c421907480a0e5aa9b1fb81962d53e19' 
  AND token = '9HgUcTlqj0NyzvS5ptbYSdA/XDJNrPtu7AnoV09xbIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}