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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453830b3dee43c73d4a6b64bbf9d112542f1d48b74f4f015721e2d70fc0ffd6b' 
  AND token = 'tW+55RpimocqpW1QoqzDwqQukxJA2eCRFI+1ZIp8YSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}