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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e1d20a0e583c0e55023430a130798ff13fdce8ddaf228952c26334e578fdb6' 
  AND token = 'dWOwpEi6vG1+SRu5yjKOjHsKUM449/T6gvxH4jVyWY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}