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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456f29f58a191b16c4fd7000565208e2c5ad9c4720140efa66192f0b1127da55' 
  AND token = '4Ex3Hr7XyTPjUyKNsHem89tltLjKEn1dUh9kwbU2mwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}