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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6b4f47692680f87c2a4c821d5e21e6da2c14a208b1274a40df4715c28d9b6c' 
  AND token = '8TAsBMbFLVG1qC/qoMKdA4VasmflfwHKA9ysx1iuhA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}