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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151b785cec786372f2ab8207292776cb77c094fb1b03b45e30eb472201a6aaab' 
  AND token = 'Hu1SihU5Xl+zRRT5a/rmeH3GyNPRvfc0YdwuiSS3Dxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}