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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c6aa6a51c0c40957e405cbc1c4f8a6b92c63024baa154377899ce00b6b133f' 
  AND token = 'DfL76G/LYmR5L5kA3DovpqpT31qI70GjBcyFZmhkEfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}