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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885e9a3a64be1259909fcddd68da14bf881e41d73be0ba3e7d9adb504d35a189' 
  AND token = 'On7vobMqpf1CoP2Kj3QM7B8xSebworQeryC9a/BmBro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}