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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f67e39a2d8a32c4de220b9cf4df1e6bdedc8c7e5f42914fe826b7044e56f12b' 
  AND token = 'lRX3zugJcCjeYu/xcMHtNzbhTQU5DDtFmwM7ZC182tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}