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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd57db33528add8411e984ad84dc68aa0f74c53a9f1b3f0e06a21efbeed6115ff' 
  AND token = 'abJQsmjR5Og9BDyH/GsEEjbj4XDBb2aXicFdKnMxyz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}